Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12493421 | 0.88 | APLNR (0.51) | APLNRTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL12699988 | 0.87 | APLNR (0.46) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL16735749 | 0.86 | APLNR (0.47) | APLNRTP53MEN1KMT2AMAPT | |
| SCHEMBL12496162 | 0.83 | TP53 (0.44) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL28923208 | 0.82 | APLNR (0.59) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL12493897 | 0.79 | APLNR (0.52) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL12493456 | 0.76 | MMP8 (0.50) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL30714247 | 0.76 | APLNR (0.49) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL1530735 | 0.75 | APLNR (0.65) | APLNRTP53HTR2AHTR2CMEN1 | |
| SCHEMBL12493085 | 0.74 | TP53 (0.42) | APLNRTP53HTR2AHTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |