Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | MMP13 | P45452 | 4/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468384 | 0.98 | MMP2 (0.39) | MMP2MMP9MMP8MMP13SIRT2 | |
| SCHEMBL10452252 | 0.94 | ELANE (0.36) | MMP2MMP9MMP8MMP13SIRT2 | |
| SCHEMBL15536523 | 0.92 | ELANE (0.37) | MMP2MMP9MMP8MMP13SIRT2 | |
| SCHEMBL16736010 | 0.90 | MMP2 (0.37) | MMP2MMP9MMP8MMP13SIRT2 | |
| SCHEMBL16735918 | 0.86 | ELANE (0.41) | CYP1A2ELANE | |
| SCHEMBL2710821 | 0.85 | ALDH1A1 (0.30) | — | |
| SCHEMBL15537681 | 0.82 | SIRT2 (0.35) | SIRT2CYP1A2CPT1A | |
| SCHEMBL15537706 | 0.80 | SIRT2 (0.37) | SIRT2CPT1ADUSP3NAAA | |
| SCHEMBL21958419 | 0.77 | MMP2 (0.41) | MMP2MMP9MMP8MMP13SIRT2 | |
| SCHEMBL15536698 | 0.77 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231288-A1 | IMPROVED DICARBONYL SUBSTITUTED-1-ALKENE COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2021-11-18 | — | — | WO | claimed |
| WO-2021162938-A1 | COPOLYMERS OF DICARBONYL SUBSTITUTED-1-ALKENE AND OLEFINS AND METHODS TO MAKE THEM | SIRRUS, INC. (US) | 2021-08-19 | — | — | WO | claimed |
| EP-3789408-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2021-03-10 | — | — | EP | claimed |
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| EP-3191530-B1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-11-11 | — | — | EP | claimed |
| CN-111825785-A | Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds | 赛鲁斯股份有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-107075223-B | Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds | 赛鲁斯股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| EP-3683267-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2020-07-22 | — | — | EP | claimed |
| EP-3191546-B1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-07-22 | — | — | EP | claimed |
| US-10633566-B2 | Polymers containing a 1,1-disubstituted alkene compound | SIRRUS, INC. (US) | 2020-04-28 | — | — | US | claimed |
| EP-3191546-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | claimed |
| US-20170198181-A1 | EMULSION INCLUDING POLYMERS CONTAINING A 1,1-DISUBSTITUTED ALKENE COMPOUND, ADHESIVES, COATINGS, AND METHODS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-07-13 | — | — | US | claimed |
| US-20170190807-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2017-07-06 | — | — | US | claimed |
| US-9676875-B2 | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions | SIRRUS, INC. (US) | 2017-06-13 | — | — | US | claimed |
| US-9637564-B2 | Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions | SIRRUS, INC. (US) | 2017-05-02 | — | — | US | claimed |
| US-20160096906-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-04-07 | — | — | US | claimed |
| US-20160096907-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2016-04-07 | — | — | US | claimed |
| WO-2016040012-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | claimed |
| US-20160068616-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2016-03-10 | — | — | US | claimed |
| US-9279022-B1 | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions | SIRRUS, INC. (US) | 2016-03-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633566-B2 | Polymers containing a 1,1-disubstituted alkene compound | ALG8, PCNA, PARP1 | MMP2 4010/4885MMP9 3916/4885MMP8 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.