Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | LOX | P28300 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22990174 | 0.88 | KDM4E (0.58) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL1573626 | 0.86 | KDM4E (0.72) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL22990173 | 0.85 | KDM4E (0.51) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL22990175 | 0.85 | KDM4E (0.51) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL27393119 | 0.82 | KDM4E (0.49) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL329498 | 0.82 | KDM4E (0.52) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL24214242 | 0.80 | KDM4E (0.50) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL323373 | 0.80 | KDM4E (0.50) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL23025 | 0.80 | KDM4E (0.55) | KDM4EPKMMAOAMAOBLOX | |
| SCHEMBL34548 | 0.80 | KDM4E (0.50) | KDM4EPKMMAOAMAOBLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003692-B | Process for producing difluoromethyl (2-pyridyl) sulfone | 山东东岳高分子材料有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117003692-A | Process for producing difluoromethyl (2-pyridyl) sulfone | 山东东岳高分子材料有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116730911-A | Preparation method of difluoromethyl (2-pyridyl) sulfone compound | 浙江九洲药业股份有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116031491-A | Electrolyte, electrochemical device, and electronic device | 宁德新能源科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-114763412-A | High-efficiency preparation method of phosphonate polymer and application of phosphonate polymer in high-temperature fuel cell | 天津师范大学 | 2022-07-19 | — | — | CN | claimed |
| US-20200214293-A1 | Pesticidal Mixtures Comprising A Pyrazole Compound | BASF SE (DE) | 2020-07-09 | — | — | US | claimed |
| EP-3641544-A1 | PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2020-04-29 | — | — | EP | claimed |
| WO-2018234478-A1 | PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2018-12-27 | — | — | WO | claimed |
| CN-121407102-A | Synthesis method of electro-nickel-promoted catalytic 2-aryl pyridine derivative | 延安大学 | 2026-01-27 | — | — | CN | disclosed |
| EP-4633681-A1 | AURISTATIN LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4602918-A2 | PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2025-08-20 | — | — | EP | disclosed |
| WO-2025038395-A1 | BENZOPYRIDINONES AND BENZOPYRIMIDINONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024262824-A1 | NOVEL PROCESS FOR SYNTHESIS OF POLYSUBSTITUTED PYRIDINE DERIVATIVES | 서울대학교산학협력단 | 2024-12-26 | — | — | WO | disclosed |
| US-20240207425-A1 | AURISTATIN LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | US | disclosed |
| WO-1996016963-A1 | SULFONAMIDES AND THEIR USE AS MEDICAMENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-06-06 | — | — | WO | disclosed |
| EP-0225981-B1 | SULFONE-CONTAINING HINDERED AMINES | PENNWALT CORPORATION (US) | 1990-08-16 | — | — | EP | disclosed |
| CN-87103523-A | The 5-sulfur substituted pyriding monocarboxylic herbicides | — | 1987-12-09 | — | — | CN | disclosed |
| EP-0225981-A1 | Sulfone-containing hindered amines | PENNWALT CORPORATION (US) | 1987-06-24 | — | — | EP | disclosed |
| EP-0035893-B1 | HERBICIDAL BENZENE- AND PYRIDINE-SULFONAMIDE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0035893-A2 | Herbicidal benzene- and pyridine-sulfonamide derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200214293-A1 | Pesticidal Mixtures Comprising A Pyrazole Compound | ACHE, GRIK3, CYP4B1 | KDM4E 1559/4885PKM 818/4885MAOA 972/4885 |
| US-20240207425-A1 | AURISTATIN LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | AURKA, AURKC, AURKB | KDM4E 1176/4885PKM 1813/4885MAOA 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.