Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650217 | 1.00 | KDM4E (0.55) | KDM4EPKMTDP1ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL17129 | 0.98 | KDM4E (0.53) | KDM4EPKMTDP1ALDH1A1HSD17B10 | |
| SCHEMBL1673906 | 0.80 | KDM4E (0.64) | KDM4EPKML3MBTL1NFE2L2SLC40A1 | |
| SCHEMBL329498 | 0.78 | KDM4E (0.52) | KDM4EPKMTDP1L3MBTL1NFE2L2 | |
| Valine SCHEMBL724587 | 0.78 | SLC7A5 (0.43) | KDM4EPKMTDP1ALDH1A1HSD17B10 | |
| SCHEMBL24214242 | 0.76 | KDM4E (0.50) | KDM4EPKMTDP1L3MBTL1NFE2L2 | |
| SCHEMBL34548 | 0.76 | KDM4E (0.50) | KDM4EPKMTDP1ALDH1A1HSD17B10 | |
| SCHEMBL18606310 | 0.76 | KDM4E (0.50) | KDM4EPKML3MBTL1NFE2L2SLC40A1 | |
| SCHEMBL323373 | 0.76 | KDM4E (0.50) | KDM4EPKMTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29569774 | 0.76 | KDM4E (0.50) | KDM4EPKMTDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120142523-A | Method for detecting isomer impurities in vonolamine fumarate starting material and application of method | 北京悦康科创医药科技股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-115974903-B | Preparation method of 2- (4- (tert-butyl) naphthalene-2-yl) -4, 5-tetramethyl-1, 3, 2-dioxaborane | 中钢集团南京新材料研究院有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118759068-A | Method for separating and measuring nitrate radical and nitrite radical residues in pyridine sulfonyl chloride | 浙江国邦药业有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-118084792-A | Pyrazole-5-sulfonamide derivative, and preparation method and application thereof | 安徽农业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-117510551-A | Pyridine sulfonamide iridium complex, preparation method and high-selectivity catalytic regeneration of NADH (NADH) | 烟台大学 | 2024-02-06 | — | — | CN | claimed |
| CN-112300123-B | Preparation method of voronoi intermediate | 上海天慈国际药业有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-115974903-A | Preparation method of 2- (4- (tert-butyl) naphthalene-2-yl) -4, 5-tetramethyl-1, 3, 2-dioxaborane | 中钢集团南京新材料研究院有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-112939955-B | 8- (pyridine amide) substituted coumarin compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| WO-2022183963-A1 | 8-(PICOLINAMIDE) SUBSTITUTED COUMARIN COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2022-09-09 | — | — | WO | claimed |
| CN-114195694-A | Preparation method of pyrrole compound | 广东东阳光药业有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-20030055290-A1 | Hydrogen reduction of sulfonyl chlorides to thiols | THE TEXAS A&M UNIVERSITY SYSTEM | 2003-03-20 | — | — | US | claimed |
| US-6531605-B1 | Reacting diazonium salt of aminopyridine or aminobenzene with thionyl chloride in water, electron transfer catalyst; 2-chloropyridine-3-sulfonyl chloride; avoids use of acetic acid and sulfur dioxide; no extraction isolation problems | ZENECA LIMITED (GB) | 2003-03-11 | — | — | US | claimed |
| EP-1265858-A1 | HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | claimed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | claimed |
| WO-2001066517-A1 | HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-13 | — | — | WO | claimed |
| EP-1048654-A2 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-02 | — | — | EP | claimed |
| WO-2000063177-A1 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RÜTGERS ORGANICS GMBH (DE) | 2000-10-26 | — | — | WO | claimed |
| EP-0973704-A1 | PROCESS FOR THE MANUFACTURE OF ARYLSULFONYL CHLORIDE | ZENECA LIMITED (GB) | 2000-01-26 | — | — | EP | claimed |
| WO-1998040332-A1 | PROCESS FOR THE MANUFACTURE OF ARYLSULFONYL CHLORIDE | ZENECA LIMITED (GB) | 1998-09-17 | — | — | WO | claimed |
| EP-0581738-A1 | Herbizidal pyridylsulfonyl ureas | CIBA-GEIGY AG (CH) | 1994-02-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055290-A1 | Hydrogen reduction of sulfonyl chlorides to thiols | TST, IAPP, CBS | KDM4E 1181/4885PKM 44/4885TDP1 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.