Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 13/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739531 | 0.94 | ENPP2 (0.74) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL15024490 | 0.93 | ENPP2 (0.74) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL16775405 | 0.92 | ENPP2 (0.73) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL16739406 | 0.91 | ENPP2 (0.77) | ENPP2ALDH1A1MAPTHPGDJAK2 | |
| SCHEMBL30146990 | 0.91 | ENPP2 (0.77) | ENPP2ALDH1A1MAPTHPGDJAK2 | |
| SCHEMBL16739421 | 0.88 | ENPP2 (0.84) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL672031 | 0.87 | ENPP2 (0.85) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL30442717 | 0.86 | ENPP2 (0.84) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL30443070 | 0.86 | ENPP2 (0.84) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL16739437 | 0.86 | ENPP2 (0.84) | ENPP2ALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12458627-B2 | Autotaxin inhibitors and uses thereof | DF 2024 IP ACQUISITION, LLC (US) | 2025-11-04 | — | — | US | disclosed |
| US-12268668-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2025-04-08 | — | — | US | disclosed |
| US-20240189281-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | SABRE THERAPEUTICS LLC (US) | 2024-06-13 | — | — | US | disclosed |
| US-11779568-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2023-10-10 | — | — | US | disclosed |
| US-11779568-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2023-10-10 | — | — | US | disclosed |
| US-11779568-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2023-10-10 | — | — | US | disclosed |
| US-20220265608-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2022-08-25 | — | — | US | disclosed |
| EP-4026549-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | Sabre Therapeutics LLC (US) | 2022-07-13 | — | — | EP | disclosed |
| US-11344533-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3878848-A1 | AUTOTAXIN INHIBITING INDOLE COMPOUNDS | Sabre Therapeutics LLC (US) | 2021-09-15 | — | — | EP | disclosed |
| US-9334261-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334261-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| WO-2016028686-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC DISORDERS | PHARMAKEA, INC. (US) | 2016-02-25 | — | — | WO | disclosed |
| US-20160046614-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-02-18 | — | — | US | disclosed |
| US-20160046614-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-02-18 | — | — | US | disclosed |
| US-20160046614-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-02-18 | — | — | US | disclosed |
| US-9051320-B1 | Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor | PHARMAKEA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-9051320-B1 | Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor | PHARMAKEA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-9051320-B1 | Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor | PHARMAKEA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| WO-2015077503-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11779568-B2 | Autotaxin inhibitor compounds | ENPP2, SERPINB1, SERPINE1 | ENPP2 1/4885ALDH1A1 4720/4885MAPT 293/4885 |
| US-12458627-B2 | Autotaxin inhibitors and uses thereof | ENPP2, SERPINB1, RNASE1 | ENPP2 1/4885ALDH1A1 4716/4885MAPT 580/4885 |
| US-20160046614-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | ENPP2 1/4885ALDH1A1 4720/4885MAPT 293/4885 |
| US-20240189281-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | ENPP2 1/4885ALDH1A1 4720/4885MAPT 293/4885 |
| US-11344533-B2 | Autotaxin inhibitor compounds | ENPP2, SERPINB1, SERPINE1 | ENPP2 1/4885ALDH1A1 4720/4885MAPT 293/4885 |
| US-20220265608-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | ENPP2 1/4885ALDH1A1 4720/4885MAPT 293/4885 |
| US-12268668-B2 | Autotaxin inhibitor compounds | ENPP2, SERPINB1, SERPINE1 | ENPP2 1/4885ALDH1A1 4720/4885MAPT 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.