Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | PLEC | Q15149 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171343 | 0.84 | GAA (0.39) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2741266 | 0.82 | GAA (0.43) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2741264 | 0.82 | GAA (0.43) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2741286 | 0.82 | GAA (0.43) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL16740190 | 0.80 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL16740194 | 0.79 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL18109164 | 0.79 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14963224 | 0.76 | GAA (0.40) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2741295 | 0.76 | GAA (0.37) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14963225 | 0.76 | GAA (0.40) | GAAMEN1KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071544-B1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORP (US) | 2022-07-06 | — | — | EP | disclosed |
| US-11060027-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200392406-A1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME | POLNOX CORPORATION | 2020-12-17 | — | — | US | disclosed |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-10294423-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2019-05-21 | — | — | US | disclosed |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION (US) | 2016-10-06 | — | — | US | disclosed |
| EP-3071544-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | Polnox Corporation (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077635-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORPORATION (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11060027-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | GAA 1034/4885MEN1 4348/4885KMT2A 3358/4885 |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | GAA 1034/4885MEN1 4348/4885KMT2A 3358/4885 |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | GAA 1016/4885MEN1 4123/4885KMT2A 3409/4885 |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | GAA 1034/4885MEN1 4348/4885KMT2A 3358/4885 |
| US-20200392406-A1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME | LPO, GPX4, DUOX2 | GAA 1034/4885MEN1 4348/4885KMT2A 3358/4885 |
| US-10294423-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | GAA 1016/4885MEN1 4123/4885KMT2A 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.