Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074337 | 0.97 | — | — | |
| SCHEMBL1666 | 0.76 | TDP1 (0.53) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27727604 | 0.73 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL28556505 | 0.73 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL28831553 | 0.73 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27938194 | 0.73 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL27490320 | 0.73 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL28275505 | 0.72 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL31412011 | 0.72 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL2154646 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114350093-B | Acrylic plate and preparation method thereof | 云浮市郁南县顺港高分子有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-3071544-B1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORP (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-114350093-A | Acrylic plate and preparation method thereof | 上海达君玻璃有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-11060027-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200392406-A1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME | POLNOX CORPORATION | 2020-12-17 | — | — | US | disclosed |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-10294423-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2019-05-21 | — | — | US | disclosed |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION (US) | 2016-10-06 | — | — | US | disclosed |
| EP-3071544-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | Polnox Corporation (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077635-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORPORATION (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11060027-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | TDP1 1052/4885CYP3A4 1297/4885ESR1 3343/4885 |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | TDP1 1052/4885CYP3A4 1297/4885ESR1 3343/4885 |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | TDP1 913/4885CYP3A4 1637/4885ESR1 3459/4885 |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | TDP1 1052/4885CYP3A4 1297/4885ESR1 3343/4885 |
| US-20200392406-A1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME | LPO, GPX4, DUOX2 | TDP1 1052/4885CYP3A4 1297/4885ESR1 3343/4885 |
| US-10294423-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | TDP1 913/4885CYP3A4 1637/4885ESR1 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.