Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 11/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16740663 | 0.90 | PRKCZ (1.00) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL16740643 | 0.88 | PRKCZ (0.78) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL16740616 | 0.85 | PRKCZ (0.73) | PRKCZMEN1KMT2AHSP90AA1CA12 | |
| SCHEMBL9628590 | 0.85 | PRKCZ (1.00) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL16740614 | 0.82 | PRKCZ (0.69) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL27955197 | 0.82 | PRKCZ (0.90) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL27792765 | 0.81 | PRKCZ (0.67) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL16740617 | 0.78 | PRKCZ (1.00) | PRKCZMEN1KMT2AATM | |
| SCHEMBL16740658 | 0.78 | PRKCZ (1.00) | PRKCZMEN1KMT2AHSP90AA1CA12 | |
| SCHEMBL16740590 | 0.76 | PRKCZ (0.69) | PRKCZCA12CA9PDE5AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075051-A1 | ALLOSTERIC INHIBITORS OF ATYPICAL PROTEIN KINASES C | UNIVERSITAET DES SAARLANDES (DE) | 2015-05-28 | — | — | WO | disclosed |