Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 12/20 | 1.00 |
| ▸ | CA12 | O43570 | 3/20 | 0.73 |
| ▸ | CA9 | Q16790 | 3/20 | 0.73 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27955197 | 0.87 | PRKCZ (0.90) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL9628590 | 0.87 | PRKCZ (1.00) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL23962450 | 0.78 | MEN1 (0.82) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL16740593 | 0.78 | PRKCZ (1.00) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL16740663 | 0.78 | PRKCZ (1.00) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL11124158 | 0.77 | MEN1 (0.68) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL8373384 | 0.77 | PRKCZ (0.82) | PRKCZCA12CA9MAOBMEN1 | |
| SCHEMBL8179557 | 0.77 | MEN1 (0.82) | PRKCZCA12CA9MAOAMAOB | |
| SCHEMBL554670 | 0.77 | EGFR (0.74) | PRKCZMAOBMEN1HSP90AA1GAA | |
| SCHEMBL3896190 | 0.77 | PRKCZ (0.82) | PRKCZMAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075051-A1 | ALLOSTERIC INHIBITORS OF ATYPICAL PROTEIN KINASES C | UNIVERSITAET DES SAARLANDES (DE) | 2015-05-28 | — | — | WO | disclosed |