SCHEMBL16740975

SCHEMBL16740975

NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)nc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.59
ALDH1A1 P00352 5/20 0.59
HTT P42858 3/20 0.59
MTOR P42345 2/20 0.59
TP53 P04637 2/20 0.59
BLM P54132 2/20 0.59
RAB9A P51151 2/20 0.59
THPO P40225 2/20 0.59
PMP22 Q01453 2/20 0.59
THRB P10828 1/20 0.59
MDM2 Q00987 1/20 0.59
NCOA1 Q15788 1/20 0.59
NCOA3 Q9Y6Q9 1/20 0.59
GMNN O75496 1/20 0.59
NFKB1 P19838 1/20 0.59
DNMT1 P26358 1/20 0.59
HBB P68871 1/20 0.59
MAPT P10636 3/20 0.55
KDM4E B2RXH2 2/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16740976 1.00 LMNA (0.59) LMNAALDH1A1HTTMTORTP53
SCHEMBL2580815 1.00 LMNA (0.59) LMNAALDH1A1HTTMTORTP53
SCHEMBL15668655 0.90 LMNA (0.59) LMNAALDH1A1HTTMTORTP53
SCHEMBL15668653 0.90 LMNA (0.59) LMNAALDH1A1HTTMTORTP53
SCHEMBL2585199 0.90 LMNA (0.47) LMNAALDH1A1HTTMTORTP53
SCHEMBL29066139 0.89 LMNA (0.58) LMNAALDH1A1HTTMTORTP53
SCHEMBL2584809 0.89 LMNA (0.58) LMNAALDH1A1HTTMTORTP53
SCHEMBL15972295 0.87 LMNA (0.56) LMNAALDH1A1HTTMTORTP53
SCHEMBL29035988 0.86 LMNA (0.55) LMNAALDH1A1HTTMTORTP53
SCHEMBL2402321 0.86 LMNA (0.55) LMNAALDH1A1HTTMTORTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739992-A1 DETECTION OF TARGET MOLECULES IN DRIED BIOLOGIC MATRICES SomaLogic Operating Co., Inc. (US) 2026-05-13 EP disclosed
WO-2025064457-A1 METHODS OF SOLID-PHASE NUCLEIC ACID HYBRIDIZATION SOMALOGIC OPERATING CO., INC. (US) 2025-03-27 WO disclosed
US-20250092447-A1 Methods of Solid-Phase Nucleic Acid Hybridization SOMALOGIC OPERATING CO., INC. (US) 2025-03-20 US disclosed
WO-2025010324-A1 DETECTION OF TARGET MOLECULES IN DRIED BIOLOGIC MATRICES SOMALOGIC OPERATING CO., INC. (US) 2025-01-09 WO disclosed
CN-112638845-B Improved proteomic multiplex assays 私募蛋白质体运营有限公司 2024-07-30 CN disclosed
CN-105658658-B Cytidine-5-formyl amine-modified polynucleotide composition and its correlation technique 私募蛋白质体公司 2019-11-05 CN disclosed
US-10239908-B2 Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto SOMALOGIC, INC. (US) 2019-03-26 US disclosed
US-20180201641-A1 Cytidine-5-Carboxamide Modified Nucleotide Compositions and Methods Related Thereto SOMALOGIC OPERATING CO. INC. 2018-07-19 US disclosed
US-20180201641-A1 Cytidine-5-Carboxamide Modified Nucleotide Compositions and Methods Related Thereto SOMALOGIC OPERATING CO. INC. 2018-07-19 US disclosed
EP-3330277-A2 CYTIDINE-5-CARBOXAMIDE MODIFIED NUCLEOTIDE COMPOSITIONS AND METHODS RELATED THERETO Somalogic, Inc. (US) 2018-06-06 EP disclosed
US-9938314-B2 Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto SOMALOGIC, INC. (US) 2018-04-10 US disclosed
EP-3071588-A1 CYTIDINE-5-CARBOXAMIDE MODIFIED NUCLEOTIDE COMPOSITIONS AND METHODS RELATED THERETO Somalogic, Inc. (US) 2016-09-28 EP disclosed
US-20160215013-A1 Cytidine-5-Carboxamide Modified Nucleotide Compositions and Methods Related Thereto SOMALOGIC OPERATING CO. INC. 2016-07-28 US disclosed
US-20160215013-A1 Cytidine-5-Carboxamide Modified Nucleotide Compositions and Methods Related Thereto SOMALOGIC OPERATING CO. INC. 2016-07-28 US disclosed
CN-105658658-A Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto 私募蛋白质体公司 2016-06-08 CN disclosed
WO-2015077292-A1 CYTIDINE-5-CARBOXAMIDE MODIFIED NUCLEOTIDE COMPOSITIONS AND METHODS RELATED THERETO SOMALOGIC, INC. (US) 2015-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180201641-A1 Cytidine-5-Carboxamide Modified Nucleotide Compositions and Methods Related Thereto NT5C3B, CDA, RNGTT LMNA 764/4885ALDH1A1 2775/4885HTT 1504/4885
US-10239908-B2 Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto NT5C3B, CDA, RNGTT LMNA 764/4885ALDH1A1 2775/4885HTT 1504/4885
US-20160215013-A1 Cytidine-5-Carboxamide Modified Nucleotide Compositions and Methods Related Thereto NT5C3B, CDA, RNGTT LMNA 764/4885ALDH1A1 2775/4885HTT 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.