Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.58 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.56 |
| ▸ | DTYMK | P23919 | 2/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16743926 | 1.00 | POLB (0.63) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL10034040 | 0.93 | POLB (0.72) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL17269644 | 0.93 | POLB (0.60) | POLBP2RY1ENPP1RNASELDTYMK | |
| SCHEMBL17268345 | 0.93 | POLB (0.60) | POLBP2RY1ENPP1RNASELDTYMK | |
| SCHEMBL29487848 | 0.89 | POLB (0.58) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL889285 | 0.89 | POLB (0.58) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL26031206 | 0.89 | POLB (0.58) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL29382612 | 0.88 | POLB (0.70) | POLBP2RY1ENPP1RNASELP2RY2 | |
| SCHEMBL31454757 | 0.88 | POLB (0.70) | POLBP2RY1ENPP1RNASELP2RY2 | |
| SCHEMBL78250 | 0.88 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329864-A1 | DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS | SPRING BANK PHARMACEUTICALS, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-9040234-B2 | Oligonucleotide analogs as therapeutic agents | SPRING BANK PHARMACEUTICALS, INC. (US) | 2015-05-26 | — | — | US | disclosed |