Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915333 | 0.92 | PTPRC (0.40) | PTPRCMAPTTDP1XBP1NPSR1 | |
| SCHEMBL16744416 | 0.87 | EGLN1 (0.42) | PTPRCSMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL14124972 | 0.83 | KMT2A (0.45) | MAPTMEN1KMT2AHDAC1SGMS2 | |
| SCHEMBL9915331 | 0.80 | MEN1 (0.40) | NPSR1MEN1KMT2A | |
| SCHEMBL14124985 | 0.80 | SGMS2 (0.48) | MAPTNPSR1MEN1KMT2ASGMS2 | |
| SCHEMBL14124908 | 0.79 | FOLH1 (0.46) | MEN1KMT2APTGER1 | |
| SCHEMBL22022295 | 0.78 | HPGD (0.40) | MAPTNPSR1MEN1KMT2ASMPD1 | |
| SCHEMBL16747452 | 0.78 | PTPRC (0.36) | PTPRCMAPT | |
| SCHEMBL14124973 | 0.76 | PPIA (0.48) | MAPTMEN1KMT2ASGMS2 | |
| SCHEMBL15275356 | 0.76 | MAPT (0.44) | PTPRCMAPTTDP1XBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148326-A1 | Monobactams | MGAM, MGAM2, BPGM | PTPRC 1442/4885MAPT 3674/4885TDP1 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.