Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744409 | 0.92 | PTPRC (0.43) | PTPRCMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9915331 | 0.90 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL16747452 | 0.89 | PTPRC (0.36) | PTPRCMAPTCNR2 | |
| SCHEMBL16744416 | 0.79 | EGLN1 (0.42) | PTPRC | |
| SCHEMBL16747451 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2ANPSR1 | |
| SCHEMBL9915323 | 0.78 | NR1H4 (0.41) | MEN1KMT2ACNR2 | |
| SCHEMBL9915523 | 0.78 | C5AR1 (0.39) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL14124972 | 0.75 | KMT2A (0.45) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9915381 | 0.74 | NPC1 (0.38) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL9915434 | 0.74 | NR1H4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012073138-A1 | MONOBACTAMS | PFIZER INC. (US) | 2012-06-07 | — | — | WO | disclosed |