Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL20598471 | 0.88 | TSHR (0.88) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL4605492 | 0.88 | TSHR (0.88) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL27703677 | 0.88 | TSHR (1.00) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL27787318 | 0.88 | TSHR (1.00) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL11680991 | 0.88 | TSHR (1.00) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL433990 | 0.88 | TSHR (1.00) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL9066990 | 0.88 | TSHR (1.00) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL11353823 | 0.88 | TSHR (1.00) | TSHRLTA4HCALM1TDP1THRB | |
| Benzyl Alcohol SCHEMBL147 | 0.88 | — | — | |
| Benzyl Alcohol SCHEMBL1332097 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9271927-B2 | Formulation of drugs and vaccines in the form of percutaneous injectable needles | AZUREBIO, S.L. (ES) | 2016-03-01 | — | — | US | disclosed |
| US-9150509-B2 | Lipoic acid derivatives | CORNERSTONE PHARMACEUTICALS, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-20140364502-A1 | LIPOIC ACID DERIVATIVES | CORNERSTONE PHARMACEUTICALS, INC. | 2014-12-11 | — | — | US | disclosed |
| US-20120219589-A1 | FORMULATION OF DRUGS AND VACCINES IN THE FORM OF PERCUTANEOUS INJECTABLE NEEDLES | AZUREBIO ,S.L. (ES) | 2012-08-30 | — | — | US | disclosed |
| EP-2485711-A1 | FORMULATION OF DRUGS AND VACCINES IN THE FORM OF PERCUTANEOUS INJECTABLE NEEDLES | Azurebio, S.L. (ES) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042542-A1 | FORMULATION OF DRUGS AND VACCINES IN THE FORM OF PERCUTANEOUS INJECTABLE NEEDLES | AZUREBIO, S. L. (ES) | 2011-04-14 | — | — | WO | disclosed |
| EP-1244415-A1 | SELF CURING CEMENTS | Abonetics 2000 Limited (GB) | 2002-10-02 | — | — | EP | disclosed |
| EP-1150996-A1 | NEW AMIDINOBENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | AstraZeneca AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001041713-A1 | SELF CURING CEMENTS | ABONETICS 2000 LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |
| WO-2000042059-A1 | NEW AMIDINOBENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364502-A1 | LIPOIC ACID DERIVATIVES | ALOX15, ALOX12, LIPC | TSHR 2406/4885LTA4H 84/4885KDM4E 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.