Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18205131 | 1.00 | MEN1 (0.50) | MEN1KMT2AANPEPERAP2MAPT | |
| SCHEMBL15768017 | 1.00 | MEN1 (0.50) | MEN1KMT2AANPEPERAP2MAPT | |
| SCHEMBL20357058 | 1.00 | MEN1 (0.50) | MEN1KMT2AANPEPERAP2MAPT | |
| SCHEMBL6783279 | 1.00 | MEN1 (0.50) | MEN1KMT2AANPEPERAP2MAPT | |
| SCHEMBL996901 | 0.97 | — | — | |
| SCHEMBL12381528 | 0.97 | — | — | |
| SCHEMBL12714698 | 0.97 | — | — | |
| SCHEMBL23885878 | 0.92 | — | — | |
| SCHEMBL6680924 | 0.86 | — | — | |
| SCHEMBL1043849 | 0.86 | PIK3CD (0.39) | MEN1KMT2AANPEPERAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151136-A1 | CATALYST COMPOSITION FOR POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | claimed |
| EP-4114566-A1 | CATALYST COMPOSITION FOR POLYURETHANES | Momentive Performance Materials Inc. (US) | 2023-01-11 | — | — | EP | claimed |
| CN-115243789-A | Catalyst composition for polyurethane | 迈图高新材料公司 | 2022-10-25 | — | — | CN | claimed |
| EP-2448667-B1 | ACID GAS SCRUBBING COMPOSITION AND PROCESS | NALCO CO (US) | 2019-06-26 | — | — | EP | claimed |
| EP-2640507-B1 | ACID GAS ABSORBENT COMPOSITION | NALCO CO (US) | 2019-05-08 | — | — | EP | claimed |
| EP-2448654-B1 | ACID GAS SCRUBBING COMPOSITION | NALCO CO (US) | 2019-05-01 | — | — | EP | claimed |
| US-9233338-B2 | Composition for treating acid gas | NALCO COMPANY (US) | 2016-01-12 | — | — | US | claimed |
| US-8765951-B2 | Acid gas absorbent composition | NALCO COMPANY (US) | 2014-07-01 | — | — | US | claimed |
| US-8765083-B2 | Acid gas absorbent composition | NALCO COMPANY (US) | 2014-07-01 | — | — | US | claimed |
| US-20140138578-A1 | COMPOSITION FOR TREATING ACID GAS | APERGY ESP SYSTEMS, LLC | 2014-05-22 | — | — | US | claimed |
| US-20080247976-A1 | water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water | DUEVA-KOGANOV OLGA V | 2008-10-09 | — | — | US | claimed |
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |
| US-7432379-B2 | Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | ELAN PHARMACEUTICALS, INC. (US) | 2008-10-07 | — | — | US | claimed |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | claimed |
| US-20060281733-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carvoxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | ELAN PHARMACEUTICALS, INC. | 2006-12-14 | — | — | US | claimed |
| EP-1633348-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Elan Pharmaceuticals, Inc. (US) | 2006-03-15 | — | — | EP | claimed |
| US-20050020659-A1 | Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | ELAN PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | claimed |
| WO-2004098589-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | claimed |
| EP-0311157-B1 | Dispersant | EFKA CHEMICALS BV (NL) | 1993-11-10 | — | — | EP | claimed |
| EP-0311157-A1 | Dispersant | EFKA-CHEMICALS B.V. (NL) | 1989-04-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080247976-A1 | water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water | CUTA, POLR1C, MSH6 | MEN1 1461/4885KMT2A 3806/4885ANPEP 3230/4885 |
| US-20050020659-A1 | Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | BDKRB1, BDKRB2, BRS3 | MEN1 1010/4885KMT2A 3940/4885ANPEP 1371/4885 |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | MEN1 997/4885KMT2A 4091/4885ANPEP 928/4885 |
| US-20060281733-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carvoxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | BDKRB1, BDKRB2, CNR1 | MEN1 3044/4885KMT2A 2589/4885ANPEP 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.