SCHEMBL16744916

SCHEMBL16744916

CC1(C)c2cc(-n3c4ccc(-c5cccc6c5oc5ccccc56)cc4c4cc(-c5cccc6c5oc5ccccc56)ccc43)ccc2-c2c1ccc1c2oc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 4/20 0.39
GGPS1 O95749 1/20 0.34
PGR P06401 1/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
AVPR1A P37288 1/20 0.31
ALK Q9UM73 2/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16744885 0.98 ALOX5 (0.41) ALOX5PRKDCGGPS1PGRPRMT5
SCHEMBL16744887 0.96 ALOX5 (0.40) ALOX5PRKDCGGPS1PGRPRMT5
SCHEMBL16744886 0.96 ALOX5 (0.40) ALOX5PRKDCGGPS1PGRPRMT5
SCHEMBL16744915 0.96 ALOX5 (0.40) ALOX5PRKDCGGPS1PGRPRMT5
SCHEMBL20154393 0.94 ALOX5 (0.38) ALOX5PRKDCGGPS1PGR
SCHEMBL16745081 0.93 ALOX5 (0.41) ALOX5PRKDCGGPS1PGRPTGES2
SCHEMBL16745133 0.92 ALOX5 (0.38) ALOX5PRKDCGGPS1PGR
SCHEMBL16744754 0.91 PGR (0.34) ALOX5PRKDCPGR
SCHEMBL16744740 0.91 PGR (0.34) ALOX5PRKDCPGR
SCHEMBL16744801 0.90 PGR (0.33) ALOX5PRKDCPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180138423-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO LTD (KR) 2018-05-17 US disclosed
US-9899607-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
US-9899607-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
US-20150144938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-05-28 US disclosed
US-20150144938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138423-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, ODC1 ALOX5 377/4885PRKDC 3488/4885GGPS1 587/4885
US-20150144938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, ODC1 ALOX5 377/4885PRKDC 3488/4885GGPS1 587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.