SCHEMBL167452

SCHEMBL167452

Nc1cccc2nc3ccccc3cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HPGD P15428 5/20 1.00
KMT2A Q03164 5/20 1.00
KDM4E B2RXH2 5/20 1.00
GLA P06280 4/20 1.00
POLB P06746 4/20 1.00
GAA P10253 4/20 1.00
RAB9A P51151 3/20 1.00
NPC1 O15118 2/20 1.00
LMNA P02545 2/20 1.00
PTBP1 P26599 1/20 1.00
RCE1 Q9Y256 1/20 1.00
MAPT P10636 5/20 0.56
ACHE P22303 3/20 0.56
HSD17B10 Q99714 4/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 1/20 0.52
KEAP1 Q14145 1/20 0.52
HTR3A P46098 1/20 0.52
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29863459 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKMT2AKDM4EGLA
Hydrochloric Acid SCHEMBL590693 0.98 ALDH1A1 (0.96) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL22265070 0.91 ALDH1A1 (0.83) ALDH1A1HPGDKMT2AKDM4EGLA
Proflavine SCHEMBL11072089 0.88 KMT2A (0.77) ALDH1A1HPGDKMT2AKDM4EGLA
Succinic Acid SCHEMBL23273535 0.87 ALDH1A1 (0.75) ALDH1A1HPGDKMT2AKDM4EGLA
Pyruvate SCHEMBL28702543 0.87 ALDH1A1 (0.75) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL3109534 0.85 ALDH1A1 (0.73) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL11766047 0.83 ALDH1A1 (0.71) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL8628036 0.82 KMT2A (0.70) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL1782937 0.82 KDM4E (0.70) ALDH1A1HPGDKMT2AKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4110 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036606-A Synthesis method of aminoacridine compound 南京工业大学 2026-05-15 CN claimed
EP-4640238-A1 THERAPEUTIC AGENT FOR PULMONARY DISEASE, HEPATIC DISEASE OR RENAL DISEASE, WHICH CONTAINS PGAM-CHK1 BINDING INHIBITOR Kyoto University (JP) 2025-10-29 EP claimed
CN-120202201-A Inhibitors of ubiquitin-specific protease 1 and uses thereof 深圳晶泰科技有限公司 2025-06-24 CN claimed
CN-119896733-A Compound, preparation method and medical application thereof 百泰生物药业有限公司 2025-04-29 CN claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
EP-4524568-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS Astellas Institute for Regenerative Medicine (US) 2025-03-19 EP claimed
CN-119161089-B Composite demulsifier for dewatering oil-containing scum and oil-containing scum treatment process 扬州工业职业技术学院 2025-03-11 CN claimed
CN-119349856-A Oil-containing scum comprehensive treatment process and system based on ultrasonic scum dehydration 扬州工业职业技术学院 2025-01-24 CN claimed
US-20250019752-A1 COMPOSITIONS AND METHODS FOR REDUCING MASTER MIX CONTAMINATION Life Technologies Corporation 2025-01-16 US claimed
US-20250003952-A1 SENOLYTIC DRUG SCREENING METHOD AND SENOLYTIC DRUG KYOTO UNIVERSITY (JP) 2025-01-02 US claimed
US-4819206-A Optical recording system MITSUBISHI DENKI K.K. (JP) 1989-04-04 US claimed
US-4816456-A Administration of monoamine acridines in cholinergic neuronal deficit states SUMMERS WILLIAM K (US) 1989-03-28 US claimed
EP-0303391-A2 Optical isomers of a spiroquinuclidine derivative State of IsraelRepresented by the Prime Minister's OfficeThe Israel Institute for Biological Research (IL) 1989-02-15 EP claimed
US-4788063-A FATTY ACID, CHOLINERGIC OR ANTICHOLINERGIC AGENT STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1988-11-29 US claimed
WO-1988002256-A1 THE ADMINISTRATION OF MONOAMINE ACRIDINES IN CHOLINERGIC NEURONAL DEFICIT STATES SUMMERS WILLIAM KOOPMANS (US) 1988-04-07 WO claimed
EP-0205247-A2 Derivatives of quinuclidine STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1986-12-17 EP claimed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP claimed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US claimed
US-4258116-A ORGANIC SEMICONDUCTOR CANON KABUSHIKI KAISHA (JP) 1981-03-24 US claimed
US-4065315-A Phototropic dye system and photosensitive compositions containing the same DYNACHEM CORPORATION (US) 1977-12-27 US claimed