SCHEMBL1782937

SCHEMBL1782937

Nc1ccc2nc3cccc(N)c3cc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.70
KMT2A Q03164 6/20 0.70
ALDH1A1 P00352 5/20 0.70
POLB P06746 5/20 0.70
LMNA P02545 5/20 0.70
GLA P06280 3/20 0.70
HPGD P15428 3/20 0.70
RAB9A P51151 3/20 0.70
NPC1 O15118 2/20 0.70
GAA P10253 2/20 0.70
PTBP1 P26599 1/20 0.70
RCE1 Q9Y256 1/20 0.70
HTR3A P46098 1/20 0.47
PLAU P00749 2/20 0.46
MAPT P10636 4/20 0.44
HSD17B10 Q99714 4/20 0.44
MEN1 O00255 3/20 0.44
TDP2 O95551 1/20 0.44
NSD2 O96028 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16736493 0.98 KDM4E (0.68) KDM4EKMT2AALDH1A1POLBLMNA
Sulfuric Acid SCHEMBL11634653 0.91 ALDH1A1 (0.58) KDM4EKMT2AALDH1A1POLBLMNA
SCHEMBL8628036 0.85 KMT2A (0.70) KDM4EKMT2AALDH1A1POLBLMNA
Hydrochloric Acid SCHEMBL28888962 0.84 KMT2A (0.68) KDM4EKMT2AALDH1A1POLBLMNA
Proflavine SCHEMBL11072089 0.83 KMT2A (0.77) KDM4EKMT2AALDH1A1POLBLMNA
SCHEMBL29863459 0.82 ALDH1A1 (1.00) KDM4EKMT2AALDH1A1POLBLMNA
SCHEMBL167452 0.82 ALDH1A1 (1.00) KDM4EKMT2AALDH1A1POLBLMNA
SCHEMBL9406881 0.82 POLB (0.66) KDM4EKMT2AALDH1A1POLBLMNA
SCHEMBL28998723 0.82 KDM4E (0.66) KDM4EKMT2AALDH1A1POLBLMNA
Hydrochloric Acid SCHEMBL590693 0.81 ALDH1A1 (0.96) KDM4EKMT2AALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150148292-A1 BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO UNIV EMORY (US) 2015-05-28 US claimed
WO-2014011540-A1 BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO EMORY UNIVERSITY (US) 2014-01-16 WO claimed
EP-4596659-A1 LIQUID FUEL PRODUCTION SYSTEM AND METHOD FOR PRODUCING LIQUID FUEL Chiyoda Corporation (JP) 2025-08-06 EP disclosed
US-20250084541-A1 CARBON DIOXIDE RECOVERY SYSTEM OSAKA UNIVERSITY (JP) 2025-03-13 US disclosed
EP-4375398-A1 CARBON DIOXIDE RECOVERY SYSTEM Chiyoda Corporation (JP) 2024-05-29 EP disclosed
WO-2024070011-A1 LIQUID FUEL PRODUCTION SYSTEM AND METHOD FOR PRODUCING LIQUID FUEL 千代田化工建設株式会社 2024-04-04 WO disclosed
WO-2023003029-A1 CARBON DIOXIDE RECOVERY SYSTEM 千代田化工建設株式会社 2023-01-26 WO disclosed
US-10933169-B2 Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto EMORY UNIVERSITY (US) 2021-03-02 US disclosed
US-10434220-B2 Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto EMORY UNIVERSITY (US) 2019-10-08 US disclosed
CN-106752954-B CCB high sealing water-repellent paint 广东鼎新高新科技股份有限公司 2019-04-02 CN disclosed
CN-106752954-A CCB high sealing water-repellent paints 广东鼎新高新科技股份有限公司 2017-05-31 CN disclosed
US-20110287312-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-11-24 US disclosed
US-20110250511-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-10-13 US disclosed
US-20110143223-A1 FUEL CELL SONY CORPORATION (JP) 2011-06-16 US disclosed
US-20110117453-A1 FUEL REFORMER AND POWER GENERATION APPARATUS USING THE SAME SONY CORPORATION (JP) 2011-05-19 US disclosed
WO-2009141301-A1 METHOD FOR DETERMINING THE DNA REPAIR CAPACITY OF A CELL PANGAEA BIOTECH, S.A. (ES) 2009-11-26 WO disclosed
EP-2123770-A1 Method for determining the DNA repair capacity of a cell Pangaea Biotech, S.A. (ES) 2009-11-25 EP disclosed
EP-1288238-A1 Compositions of matter having bioactive properties Schmitz, Robert A. (US) 2003-03-05 EP disclosed
US-6299892-B1 INCORPORATING INTO DELIVERY VEHICLES SUITABLE FOR EFFECTING DESIRED ANTIMICROBIAL USE, SOAPS AND DETERGENTS SCHMITZ ROBERT A (US) 2001-10-09 US disclosed
US-4060527-A MICROBIOCIDE FUJI CHEMICAL INDUSTRIES, LTD. (JA) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148292-A1 BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO BMP4, BMP2, BMP1 KDM4E 1908/4885KMT2A 4390/4885ALDH1A1 3881/4885
US-10434220-B2 Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto BMP2, BMP4, BMP1 KDM4E 1495/4885KMT2A 3326/4885ALDH1A1 1840/4885
US-10933169-B2 Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto BMP2, BMP4, BMP1 KDM4E 1495/4885KMT2A 3326/4885ALDH1A1 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.