Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749785 | 0.85 | CYP2C19 (0.64) | TSHRCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8947206 | 0.84 | CYP1A2 (0.58) | TSHRCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL16746723 | 0.81 | CYP1A2 (0.47) | TSHRCYP1A2HPGDALOX12HSD17B10 | |
| SCHEMBL12147020 | 0.78 | TSHR (0.47) | TSHRCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL27016948 | 0.74 | CYP1A2 (0.82) | TSHRCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8623371 | 0.74 | MEN1 (0.65) | TSHRCYP3A4HSD17B10MAPTMEN1 | |
| SCHEMBL29903883 | 0.74 | MEN1 (0.65) | TSHRCYP3A4HSD17B10MAPTMEN1 | |
| SCHEMBL29450699 | 0.74 | MEN1 (0.65) | TSHRCYP3A4HSD17B10MAPTMEN1 | |
| SCHEMBL21433105 | 0.73 | CYP1A2 (0.56) | TSHRCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9719317 | 0.72 | ALDH1A1 (0.53) | TSHRCYP3A4CYP1A2CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346958-B2 | Reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150143639-A1 | Reactive Dyes, Their Preparation and Their Use | HUNTSMAN INTERNATIONAL LLC | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150143639-A1 | Reactive Dyes, Their Preparation and Their Use | H1-2, H1-3, H1-4 | TSHR 373/4885CYP3A4 1795/4885CYP1A2 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.