SCHEMBL1674737

SCHEMBL1674737

CC1=C(C)c2c(C)cc(C)c(C)c2[CH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7076866 0.67
SCHEMBL2051464 0.67
SCHEMBL814919 0.63 CYP3A4 (0.37)
SCHEMBL1674749 0.62 RAPGEF4 (0.33)
SCHEMBL16980234 0.62 TDP2 (0.42)
SCHEMBL3693275 0.60 CYP3A4 (0.35)
SCHEMBL3695633 0.60 CYP3A4 (0.35)
SCHEMBL29597791 0.60 CYP3A4 (0.30)
SCHEMBL120101 0.59 TSHR (0.39)
SCHEMBL13899602 0.58 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377613-B1 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-19 EP disclosed
EP-1412398-B1 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-24 EP disclosed
CN-101143908-B Olefin polymer DOW GLOBAL TECHNOLOGIES INC. (US) 2011-12-14 CN disclosed
US-RE43004-E1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-06 US disclosed
US-7999039-B2 Catalytic polymerization of olefinic monomers in the presence of a high molecular weight catalyst and a low molecular weight catalyst in a polymerization reactor system; high melt strength DOW GLOBAL TECHNOLOGIES LLC (US) 2011-08-16 US disclosed
US-RE42276-E1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-04-05 US disclosed
CN-100519588-C Method of making polymer and polymer composition DOW GLOBAL TECHNOLOGIES INC (US) 2009-07-29 CN disclosed
CN-101143908-A Olefin polymer DOW GLOBAL TECHNOLOGIES INC (US) 2008-03-19 CN disclosed
US-7300983-B2 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-27 US disclosed
US-7271221-B2 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2007-09-18 US disclosed
US-6455458-B1 HIGH MOLECULAR WEIGHT POLYOLEFIN; GROUP 4 TRANSITION METAL COMPLEXES HAVING A BIDENTATE ANCILLARY LIGAND SYSTEM OF ONE CYCLOPENTADIENYL GROUP BOUND TO THE TRANSITION METAL AND A GROUP 15 OR GROUP 16 ATOM COVALENTLY BOUND THROUGH A BRIDGING EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-24 US disclosed
US-6420507-B1 COORDINATION CATALYSTS FOR POLYMERS THE DOW CHEMICAL COMPANY 2002-07-16 US disclosed
EP-0910593-B1 ELASTOMERS AND PROCESS FOR THEIR MANUFACTURE DOW CHEMICAL CO (US) 2001-04-18 EP disclosed
CN-1258303-A Olefin polymers prepared with substituted indenyl containing metal complexes DOW CHEMICAL CO (US) 2000-06-28 CN disclosed
EP-0977787-A1 OLEFIN POLYMERS PREPARED WITH SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-02-09 EP disclosed
US-6015868-A CATALYSIS OF HIGH TEMPERATURE, SOLUTION POLYMERIZATION WHICH YIELDS HIGH MOLECULAR WEIGHT OLEFIN POLYMERS, BY USING COORDINATION CATALYST MIXED WITH AN ACTIVATING COCATALYST, EFFICIENCY THE DOW CHEMICAL COMPANY (US) 2000-01-18 US disclosed
CN-1200735-A Substituted indenyl contg. metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 1998-12-02 CN disclosed
WO-1998049211-A1 OLEFIN POLYMERS PREPARED WITH SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1998-11-05 WO disclosed
EP-0874860-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1998-11-04 EP disclosed
WO-1997015583-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-05-01 WO disclosed