Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 6/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.37 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796918 | 0.84 | TXNRD1 (0.39) | MAPTTXNRD1PIN1FGFR4RPS6KB2 | |
| SCHEMBL796948 | 0.82 | MAPT (0.43) | MAPTTXNRD1ALDH1A1PIN1FGFR4 | |
| SCHEMBL203781 | 0.75 | PDE10A (0.50) | MAPTALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL23878654 | 0.74 | MERTK (0.40) | MAPTPIN1FGFR4RPS6KB2MERTK | |
| SCHEMBL18658901 | 0.73 | NR4A2 (0.45) | MAPT | |
| SCHEMBL30775559 | 0.72 | PIK3CD (0.35) | MAPT | |
| SCHEMBL110092 | 0.70 | MAPT (0.47) | MAPTTXNRD1ALDH1A1DHFRFGFR4 | |
| SCHEMBL29677457 | 0.70 | MAPT (0.47) | MAPTTXNRD1ALDH1A1DHFRFGFR4 | |
| SCHEMBL31458500 | 0.69 | MEN1 (0.50) | MAPTALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL9499655 | 0.69 | MEN1 (0.50) | MAPTALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074516-A1 | KETONE DERIVATIVES OF IMIDAZOLES, PHARMACEUTICAL COMBINATIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 | 2015-05-28 | — | — | WO | disclosed |