Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 9/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15185777 | 0.93 | KDM4E (0.43) | GABRG2GABRB3GABRA2KDM4EALDH1A1 | |
| SCHEMBL2634478 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10L3MBTL1MAOB | |
| Hydrochloric Acid SCHEMBL2634079 | 0.89 | KMT2A (0.44) | KDM4EALDH1A1HSD17B10L3MBTL1MAOB | |
| SCHEMBL15185775 | 0.85 | CA12 (0.44) | GABRG2GABRB3GABRA2KDM4EALDH1A1 | |
| SCHEMBL9608994 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10L3MBTL1KMT2A | |
| Trifluoroacetic Acid SCHEMBL30286292 | 0.81 | CSNK1D (0.43) | KDM4EALDH1A1HSD17B10L3MBTL1MAOB | |
| SCHEMBL16541800 | 0.80 | SCNN1A (0.53) | KDM4EALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL1429031 | 0.78 | SCNN1A (0.50) | KDM4EALDH1A1HSD17B10MAOBCYP1A2 | |
| SCHEMBL12516426 | 0.78 | KDM4E (0.38) | GABRG2GABRB3GABRA2KDM4EALDH1A1 | |
| SCHEMBL13510973 | 0.77 | TDP1 (0.41) | ALDH1A1L3MBTL1MAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150147277-A1 | COMPOSITIONS AND METHODS FOR ASSESSING GUT FUNCTION | MEDIBEACON INC. | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147277-A1 | COMPOSITIONS AND METHODS FOR ASSESSING GUT FUNCTION | FABP2, SLC10A2, SI | GABRG2 2750/4885GABRB3 3254/4885GABRA2 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.