Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | CCR6 | P51684 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050527 | 1.00 | KDM4E (0.59) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL168649 | 0.95 | KDM4E (0.57) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL29452704 | 0.95 | KDM4E (0.57) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL31606573 | 0.94 | KDM4E (0.55) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL9248724 | 0.88 | PKM (0.57) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL167829 | 0.84 | KDM4E (0.52) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL614662 | 0.83 | KDM4E (0.54) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL168947 | 0.83 | KDM4E (0.62) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL571223 | 0.82 | KDM4E (0.59) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL342559 | 0.81 | PKM (0.67) | KDM4EALOX12CYP3A4TDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1092 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| WO-2004065366-A1 | 2.4-DIHALOGEN-6-(C2-C3-ALKYL)-PHENYL SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | claimed |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | BAYER CROPSCIENCE K.K. (JP) | 2004-07-08 | — | — | US | claimed |
| EP-1429613-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND SAFENERS | Bayer CropScience AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1367888-A2 | SELECTIVE SUBSTITUTED ARYL KETONE AND SAFENER BASED HERBICIDES | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | claimed |
| US-20030211942-A1 | Aryl sulfonyl amino carbonyl triazole based selective herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-11-13 | — | — | US | claimed |
| EP-1303189-A1 | ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES | Bayer CropScience AG (DE) | 2003-04-23 | — | — | EP | claimed |
| WO-2003026427-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2003-04-03 | — | — | WO | claimed |
| WO-2002063957-A2 | SELECTIVE SUBSTITUTED ARYL KETONE AND SAFENER BASED HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-08-22 | — | — | WO | claimed |
| WO-2002001957-A1 | ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-01-10 | — | — | WO | claimed |
| US-6124240-A | Combinations of sulfonylurea herbicides and safeners | HOECHST AGREVO GMBH (DE) | 2000-09-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030211942-A1 | Aryl sulfonyl amino carbonyl triazole based selective herbicides | AADAC, CBR3, ABAT | KDM4E 1867/4885ALOX12 2886/4885CYP3A4 810/4885 |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | CYP2W1, CYP4Z1, CYP2E1 | KDM4E 1001/4885ALOX12 1017/4885CYP3A4 54/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | KDM4E 2075/4885ALOX12 1253/4885CYP3A4 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.