SCHEMBL168649

SCHEMBL168649

CCOC(=O)C(Oc1ccc(Cl)c2cccnc12)C(=O)OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.57
PKM P14618 1/20 0.55
ALOX12 P18054 2/20 0.54
CYP3A4 P08684 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 6/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NPSR1 Q6W5P4 3/20 0.46
HTT P42858 2/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
CCR6 P51684 2/20 0.46
HSP90AA1 P07900 2/20 0.46
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPK1 P28482 1/20 0.45
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452704 1.00 KDM4E (0.57) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL30050527 0.95 KDM4E (0.59) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL167490 0.95 KDM4E (0.59) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL31606573 0.90 KDM4E (0.55) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL9248724 0.84 PKM (0.57) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL167829 0.81 KDM4E (0.52) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL6904223 0.80 KDM4E (0.51) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL614662 0.79 KDM4E (0.54) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL168947 0.79 KDM4E (0.62) KDM4EPKMALOX12CYP3A4TDP1
SCHEMBL571223 0.79 KDM4E (0.59) KDM4EPKMALOX12CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011138280-A2 HERBICIDE/SAFENER COMBINATIONS COMPRISING ARYLPYRIDAZINONES AND SAFENER BAYER CROPSCIENCE AG (DE) 2011-11-10 WO claimed
EP-2210492-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-07-28 EP claimed
EP-2191720-A1 Herbicide-safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-2191716-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2026-05-21 US disclosed
US-12599136-B2 Substituted isophthalic acid diamides and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-14 US disclosed
EP-4680598-A1 4-DIFLUOROMETHYL BENZAMIDES WITH HERBICIDAL ACTION Bayer Aktiengesellschaft (DE) 2026-01-21 EP disclosed
US-12509445-B2 Herbicidally active 4-cyclopropyl-6-[4-(trifluormethyl)pyrazol-1-yl)]pyrimidines BAYER AKTIENGESELLSCHAFT (DE) 2025-12-30 US disclosed
EP-4665151-A1 HERBICIDAL MIXTURES Bayer Aktiengesellschaft (DE) 2025-12-24 EP disclosed
US-12492173-B2 Herbicidal substituted N-tetrazolyl aryl carboxamides BAYER AKTIENGESELLSCHAFT (DE) 2025-12-09 US disclosed
US-20250311727-A1 SUBSTITUTED 2-AMINOAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-10-09 US disclosed
EP-0790771-B1 COMBINATIONS OF PHENYLSULPHONYL UREA HERBICIDES AND SAFENERS HOECHST SCHERING AGREVO GMBH (DE) 1999-01-20 EP disclosed
EP-0721299-B1 NEW MIXTURES OF HERBICIDES AND ANTIDOTES HOECHST SCHERING AGREVO GMBH (DE) 1998-12-02 EP disclosed
WO-1998024320-A1 HERBICIDES CONTAINING N-[(4,6-DIMETHOXYPYRIMIDINE-2-YL)AMINOCARBONYL]-5-METHYLSULPHONAMIDOMETHYL -2-ALKOXYCARBONYLBENZENE SULPHONAMIDES HOECHST SCHERING AGREVO GMBH (DE) 1998-06-11 WO disclosed
WO-1998011781-A1 COMBINATIONS OF SULFONYL UREA HERBICIDES AND SAFENERS HOECHST SCHERING AGREVO GMBH (DE) 1998-03-26 WO disclosed
EP-0790771-A1 COMBINATIONS OF PHENYLSULPHONYL UREA HERBICIDES AND SAFENERS Hoechst Schering AgrEvo GmbH (DE) 1997-08-27 EP disclosed
EP-0721299-A1 NEW MIXTURES OF HERBICIDES AND ANTIDOTES Hoechst Schering AgrEvo GmbH (DE) 1996-07-17 EP disclosed
WO-1996014747-A1 COMBINATIONS OF PHENYLSULPHONYL UREA HERBICIDES AND SAFENERS HOECHST SCHERING AGREVO GMBH (DE) 1996-05-23 WO disclosed
WO-1995008919-A1 NEW MIXTURES OF HERBICIDES AND ANTIDOTES HOECHST SCHERING AGREVO GMBH (DE) 1995-04-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES CBR1, CBR3, HDHD5 KDM4E 3156/4885PKM 1938/4885ALOX12 3049/4885
US-20250311727-A1 SUBSTITUTED 2-AMINOAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES DDC, WIZ, DDT KDM4E 565/4885PKM 1854/4885ALOX12 1175/4885
US-12492173-B2 Herbicidal substituted N-tetrazolyl aryl carboxamides DDT, CYP4X1, AADAC KDM4E 1244/4885PKM 2789/4885ALOX12 2804/4885
US-12509445-B2 Herbicidally active 4-cyclopropyl-6-[4-(trifluormethyl)pyrazol-1-yl)]pyrimidines CBR3, CBR1, HAX1 KDM4E 488/4885PKM 2961/4885ALOX12 3664/4885
US-12599136-B2 Substituted isophthalic acid diamides and their use as herbicides P4HA1, DDT, CNPY2 KDM4E 2659/4885PKM 3574/4885ALOX12 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.