SCHEMBL16749658

SCHEMBL16749658

CC(c1ccc2c(c1)C(=O)c1ccccc1C2=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.46
ALDH1A1 P00352 5/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
MAPK1 P28482 4/20 0.46
MAPT P10636 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 2/20 0.46
ELANE P08246 1/20 0.46
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
PKM P14618 1/20 0.44
HTT P42858 1/20 0.44
PARG Q86W56 4/20 0.43
CASP3 P42574 2/20 0.42
SENP8 Q96LD8 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
TTR P02766 1/20 0.42
PLA2G1B P04054 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749661 0.89 ELANE (0.54) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL18378329 0.80 ELANE (0.46) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL11848869 0.78 HTR6 (0.44) SMN1; SMN2ALDH1A1MAPTLMNAKMT2A
SCHEMBL18378332 0.76 NPC1 (0.46) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL188872 0.76 ELANE (0.57) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL31107058 0.74 ELANE (0.55) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL18138411 0.74 ELANE (0.55) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL13310639 0.74 ELANE (0.55) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1
SCHEMBL6510279 0.74 KEAP1 (0.44) ALDH1A1MAPTLMNAKMT2ACYP3A4
SCHEMBL17710508 0.73 ELANE (0.53) SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
CN-105764885-A Acid- and radical-generating agent and method for generating acid and radical 和光纯药工业株式会社 2016-07-13 CN disclosed
WO-2015076395-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL 和光純薬工業株式会社 2015-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 SMN1; SMN2 3268/4885ALDH1A1 151/4885NPC1 3627/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 SMN1; SMN2 3268/4885ALDH1A1 151/4885NPC1 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.