Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 12/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 12/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12816498 | 1.00 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BTEAD3ADRB2 | |
| SCHEMBL16749903 | 0.90 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BTEAD3ADRB2 | |
| SCHEMBL12247877 | 0.88 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BTEAD3ADRB2 | |
| SCHEMBL17502988 | 0.88 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BTEAD3ADRB2 | |
| Mandelic Acid SCHEMBL15921346 | 0.87 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BTEAD3ADRB2 | |
| SCHEMBL3342398 | 0.86 | TEAD3 (0.39) | ADRA1DADRA1AADRA1BTEAD3MEN1 | |
| SCHEMBL15921877 | 0.86 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BTEAD3ADRB2 | |
| SCHEMBL18157055 | 0.83 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL15934399 | 0.83 | HRH3 (0.36) | ADRA1DADRA1AADRA1BTEAD3MEN1 | |
| SCHEMBL16749915 | 0.83 | ACHE (0.42) | ADRA1DADRA1AADRA1BTEAD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394251-B2 | Silodosin intermediate and preparation method therefor | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2016-07-19 | — | — | US | disclosed |
| US-20150148548-A1 | Silodosin Intermediate and Preparation Method Therefor | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148548-A1 | Silodosin Intermediate and Preparation Method Therefor | CYP51A1, VIP, CYP4F11 | ADRA1D 196/4885ADRA1A 436/4885ADRA1B 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.