Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13893128 | 0.81 | LMNA (0.34) | MEN1KMT2AKDM4EMAPK1CA2 | |
| SCHEMBL8991727 | 0.81 | ALDH1A1 (0.47) | KDM4ECA2CA12CA1CA4 | |
| SCHEMBL14274646 | 0.79 | PAOX (0.40) | PAOXMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL18545062 | 0.79 | CA1 (0.32) | PAOXMEN1KMT2ACA2CA1 | |
| SCHEMBL24972126 | 0.78 | PAOX (0.50) | PAOXMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL18127638 | 0.78 | PAOX (0.50) | PAOXMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL9987483 | 0.78 | PAOX (0.50) | PAOXMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL11963633 | 0.78 | PAOX (0.50) | PAOXMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL21130883 | 0.78 | PAOX (0.50) | PAOXMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL2801261 | 0.78 | PAOX (0.50) | PAOXMEN1KMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075699-A1 | DOTAM DERIVATIVES FOR THERAPEUTIC USE | SANOFI (FR) | 2015-05-28 | — | — | WO | disclosed |