Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 4/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025057 | 0.86 | SCN9A (0.52) | CA2F10F2PRSS1PRSS2 | |
| SCHEMBL6974699 | 0.82 | ALOX5AP (0.53) | — | |
| SCHEMBL6303171 | 0.81 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6303170 | 0.80 | MKNK1 (0.54) | CA2F10F2PRSS1PRSS2 | |
| SCHEMBL4535022 | 0.78 | KDM1A (0.53) | RORCCA2 | |
| SCHEMBL7265178 | 0.77 | PTGS2 (0.50) | CA2PTGS2 | |
| SCHEMBL7090663 | 0.76 | PRMT1 (0.58) | RORCCA2F10 | |
| SCHEMBL18234492 | 0.76 | — | — | |
| SCHEMBL6801877 | 0.75 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL3830209 | 0.75 | PTGS2 (0.48) | CA2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |