Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 16/20 | 0.53 |
| ▸ | FEN1 | P39748 | 16/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190899 | 0.85 | ALOX5AP (0.55) | ALOX5APFEN1MMP3OPRM1OPRK1 | |
| SCHEMBL6630002 | 0.83 | ALOX5AP (0.57) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL7355753 | 0.82 | ALOX5AP (0.49) | ALOX5APFEN1MMP3OPRM1OPRK1 | |
| SCHEMBL7355749 | 0.82 | SCN9A (0.48) | ALOX5APFEN1MMP3OPRM1OPRK1 | |
| SCHEMBL7355759 | 0.82 | ALOX5AP (0.49) | ALOX5APFEN1MMP3OPRM1OPRK1 | |
| SCHEMBL1675591 | 0.82 | RORC (0.43) | — | |
| SCHEMBL7266847 | 0.81 | ALOX5AP (0.55) | ALOX5APFEN1MMP3OPRM1OPRK1 | |
| SCHEMBL2280981 | 0.81 | ALOX5AP (0.54) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL7025057 | 0.80 | SCN9A (0.52) | — | |
| SCHEMBL6628076 | 0.80 | ALOX5AP (0.59) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |