Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.66 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359941 | 0.94 | MTNR1A (0.63) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL5359373 | 0.94 | MTNR1A (0.63) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL11622077 | 0.84 | LOXL2 (0.71) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL867547 | 0.84 | LOXL2 (0.75) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL7952644 | 0.83 | LOXL2 (0.69) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL28379600 | 0.81 | LOXL2 (0.67) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL6803154 | 0.81 | LOXL2 (0.77) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL9197050 | 0.81 | LOXL2 (0.58) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL8946252 | 0.81 | MTNR1A (0.67) | MTNR1ALOXL2MTNR1BHRH3AXL | |
| SCHEMBL2157095 | 0.79 | LOXL2 (0.73) | MTNR1ALOXL2MTNR1BHRH3AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978527-A | Delta-carboline compound and synthetic method and application thereof | 中国科学院成都生物研究所 | 2024-11-19 | — | — | CN | disclosed |
| US-9061994-B1 | Materials and methods useful to induce vacuolization, cell death, or a combination thereof | THE UNIVERSITY OF TOLEDO (US) | 2015-06-23 | — | — | US | disclosed |
| US-20150152049-A1 | Materials And Methods Useful To Induce Vacuolization, Cell Death, Or A Combination Thereof | THE UNIVERSITY OF TOLEDO (US) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152049-A1 | Materials And Methods Useful To Induce Vacuolization, Cell Death, Or A Combination Thereof | BECN1, BAD, BAX | MTNR1A 2714/4885LOXL2 1188/4885MTNR1B 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.