Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.60 |
| ▸ | AXL | P30530 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507809 | 0.87 | LOXL2 (1.00) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL867547 | 0.86 | LOXL2 (0.75) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL7952644 | 0.85 | LOXL2 (0.69) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL28379600 | 0.84 | LOXL2 (0.67) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL2157095 | 0.81 | LOXL2 (0.73) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL16756016 | 0.81 | MTNR1A (0.66) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL4563834 | 0.81 | LOXL2 (0.63) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL8946252 | 0.80 | MTNR1A (0.67) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL11622077 | 0.80 | LOXL2 (0.71) | LOXL2HRH3MTNR1AMTNR1BAXL | |
| SCHEMBL11160135 | 0.80 | LOXL2 (0.71) | LOXL2HRH3MTNR1AMTNR1BAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224960-A1 | Pharmaceutical compositions and methods for their use | AGOURON PHARMACEUTICALS, INC. | 2004-11-11 | — | — | US | claimed |
| US-3930948-A | ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES | AJINOMOTO CO., INC. (JA) | 1976-01-06 | — | — | US | claimed |
| WO-2019238057-A1 | APPLICATION OF FSO2N3 IN PREPARATION OF AZIDE | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |
| US-20040224960-A1 | Pharmaceutical compositions and methods for their use | AGOURON PHARMACEUTICALS, INC. | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224960-A1 | Pharmaceutical compositions and methods for their use | CYP3A5, CYP3A7, CYP3A43 | LOXL2 2476/4885HRH3 2325/4885MTNR1A 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.