Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757219 | 0.77 | CYP1A2 (0.34) | SMN1; SMN2 | |
| SCHEMBL16760697 | 0.76 | TDP1 (0.31) | — | |
| SCHEMBL29132569 | 0.74 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL17961794 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2FKBP1A | |
| SCHEMBL17961792 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2FKBP1A | |
| SCHEMBL16579348 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2FKBP1A | |
| SCHEMBL16579389 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2FKBP1A | |
| SCHEMBL31153913 | 0.69 | RECQL (0.38) | SMN1; SMN2 | |
| SCHEMBL29132593 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2FKBP1A | |
| SCHEMBL27089375 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074402-A1 | BICYCLOAMINE-SUBSTITUTED-N-BENZENESULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS | Merck Sharp & Dohme Corp. (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015077905-A1 | BICYCLOAMINE-SUBSTITUTED-N-BENZENESULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS | MERCK SHARP & DOHME CORP. (US) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015080988-A1 | BICYCLOAMINE-SUBSTITUTED-N-BENZENESULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS | MERCK SHARP & DOHME CORP. (US) | 2015-06-04 | — | — | WO | disclosed |