Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26112047 | 0.95 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TP53GAAMEN1 | |
| SCHEMBL26117512 | 0.88 | MAPT (0.42) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL1147987 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TP53GAAMEN1 | |
| SCHEMBL1700418 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TP53GAAMEN1 | |
| SCHEMBL29132569 | 0.81 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL21851141 | 0.78 | TP53 (0.56) | SMN1; SMN2ALDH1A1TP53GAAMEN1 | |
| SCHEMBL15570547 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1TP53GAAMEN1 | |
| SCHEMBL17374329 | 0.77 | CHRNB2 (0.39) | SMN1; SMN2ALDH1A1FKBP1A | |
| SCHEMBL3652002 | 0.73 | MEN1 (0.40) | ALDH1A1GAAMEN1KMT2AHTT | |
| SCHEMBL18982926 | 0.73 | FKBP1A (0.35) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829570-A | WEE1 degrading compounds | 北京星奇原生物科技有限公司 | 2023-09-29 | — | — | CN | disclosed |