SCHEMBL29132569

SCHEMBL29132569

COC(=O)C1CCC(N2CCC(CO[Si](C)(C)C(C)(C)C)CC2)CC1N1CCC(CO[Si](C)(C)C(C)(C)C)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26112047 0.83 SMN1; SMN2 (0.38) FKBP1A
SCHEMBL29132593 0.81 SMN1; SMN2 (0.41) FKBP1A
SCHEMBL16757264 0.74 SMN1; SMN2 (0.30) FKBP1A
SCHEMBL26117512 0.72 MAPT (0.42)
SCHEMBL1700418 0.72 SMN1; SMN2 (0.39) FKBP1A
SCHEMBL1147987 0.72 SMN1; SMN2 (0.39) FKBP1A
SCHEMBL17374329 0.70 CHRNB2 (0.39) FKBP1A
SCHEMBL21987460 0.69 FKBP1A (0.36) FKBP1A
SCHEMBL581410 0.68 TSHR (0.37) FKBP1A
SCHEMBL16096341 0.67 RBP4 (0.39) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116829570-A WEE1 degrading compounds 北京星奇原生物科技有限公司 2023-09-29 CN disclosed