SCHEMBL167573

SCHEMBL167573

O=C(O)NCc1ccc(Cl)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
CYP2C9 P11712 2/20 0.68
CYP2C19 P33261 2/20 0.68
ALDH1A1 P00352 6/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
HPGD P15428 3/20 0.59
GAA P10253 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.56
PLAAT3 P53816 1/20 0.56
PLAAT5 Q96KN8 1/20 0.56
PLAAT2 Q9NWW9 1/20 0.56
PLAAT4 Q9UL19 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
TSHR P16473 1/20 0.55
MAPT P10636 2/20 0.54
THRB P10828 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11533429 0.89 CYP2C9 (0.65) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL24576009 0.84 MEN1 (1.00) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL29665191 0.83 CYP2C9 (0.58) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL19553939 0.83 NAMPT (0.62) MEN1KMT2AALDH1A1TP53CYP1A2
SCHEMBL31366711 0.83 CYP2C9 (0.58) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL22648480 0.83 MEN1 (0.68) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL5300637 0.83 ALDH1A1 (0.59) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL3278767 0.83 CYP2C9 (0.55) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL31294636 0.83 MEN1 (0.73) MEN1KMT2ACYP2C9CYP2C19ALDH1A1
SCHEMBL15514528 0.83 MEN1 (0.73) MEN1KMT2ACYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257031-A1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL)ETHYLAMINO]ALKANEAMIDE DERIVATIVES NEWRON PHARMACEUTICALS S.P.A. (IT) 2025-08-14 US claimed
US-12291495-B2 Process for the production of substituted 2-[2-(phenyl)ethylamino] alkaneamide derivatives NEWRON PHARMACEUTICALS S.P.A. (IT) 2025-05-06 US claimed
EP-3715346-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2024-01-03 EP claimed
EP-2970107-B1 PHOTOSWITCHABLE HDAC INHIBITORS MASSACHUSETTS GEN HOSPITAL (US) 2023-11-15 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-20220185766-A1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL)ETHYLAMINO]ALKANEAMIDE DERIVATIVES NEWRON PHARMACEUTICALS S.P.A. (IT) 2022-06-16 US claimed
EP-3956296-A1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL) ETHYLAMINO]ALKANEAMIDE DERIVATIVES Newron Pharmaceuticals S.p.A. (IT) 2022-02-23 EP claimed
CN-113710645-A Process for preparing substituted 2- [2- (phenyl) ethylamino ] alkanamide derivatives 纽朗制药公司 2021-11-26 CN claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
WO-2010060578-A2 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO claimed
WO-2010060581-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO claimed
WO-2010060580-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO claimed
WO-2010060579-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO claimed
EP-2191720-A1 Herbicide-safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-2191716-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-1673337-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-06-28 EP claimed
WO-2005033066-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-04-14 WO claimed
US-4390710-A A 4-AMINOPYRIDINE WITH A PYRIDINE PPG INDUSTRIES, INC. (US) 1983-06-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185766-A1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL)ETHYLAMINO]ALKANEAMIDE DERIVATIVES HRH3, CYP2A7, HRH4 MEN1 2922/4885KMT2A 2734/4885CYP2C9 350/4885
US-20250257031-A1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL)ETHYLAMINO]ALKANEAMIDE DERIVATIVES HRH3, HRH4, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 MEN1 3089/4885KMT2A 2981/4885CYP2C9 213/4885
US-12291495-B2 Process for the production of substituted 2-[2-(phenyl)ethylamino] alkaneamide derivatives HRH3, CYP2A7, HRH4 MEN1 2922/4885KMT2A 2734/4885CYP2C9 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.