Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124270 | 0.86 | ALDH1A1 (0.66) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL1675928 | 0.83 | CA2 (0.43) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL6788342 | 0.83 | ALDH1A1 (0.61) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL1675924 | 0.82 | ALDH1A1 (0.53) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL6385785 | 0.81 | USP2 (0.56) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL14473350 | 0.80 | ALDH1A1 (0.62) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL2152758 | 0.80 | ALDH1A1 (0.57) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL17507087 | 0.80 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDMAPTLMNA | |
| SCHEMBL11142367 | 0.79 | ALDH1A1 (0.74) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL4418893 | 0.79 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| US-20220081427-A1 | INHIBITORS OF JUN N-TERMINAL KINASE | IMAGO PHARMACEUTICALS, INC. (US) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081427-A1 | INHIBITORS OF JUN N-TERMINAL KINASE | CHUK, MAPK6, MAPK3 | ALDH1A1 4529/4885USP2 1559/4885HPGD 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.