Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140240 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1USP2MAPT | |
| SCHEMBL1675932 | 0.83 | ALDH1A1 (0.59) | ALDH1A1USP2MAPTLMNAHPGD | |
| SCHEMBL3864473 | 0.75 | ALDH1A1 (0.45) | ALDH1A1USP2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL6771290 | 0.74 | ALDH1A1 (0.65) | ALDH1A1USP2MAPTHPGD | |
| SCHEMBL6140778 | 0.74 | MAPT (0.64) | ALDH1A1USP2MAPTHPGD | |
| SCHEMBL29639814 | 0.74 | ITGB3 (0.54) | CA2ITGB3ITGA2BALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5631058 | 0.73 | ALDH1A1 (0.48) | ALDH1A1USP2MAPTLMNAHPGD | |
| SCHEMBL3868815 | 0.73 | ALDH1A1 (0.48) | ALDH1A1USP2MAPTLMNA | |
| SCHEMBL2440672 | 0.72 | NPC1 (0.54) | CA2ITGB3ITGA2BALDH1A1USP2 | |
| SCHEMBL6140774 | 0.71 | KMT2A (0.43) | ALDH1A1USP2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |