Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16759581 | 1.00 | CHRM2 (0.31) | CHRM2CHRM1CHRM3DGAT1MEN1 | |
| SCHEMBL16759533 | 1.00 | CHRM2 (0.31) | CHRM2CHRM1CHRM3DGAT1MEN1 | |
| SCHEMBL10519878 | 0.86 | ARG1 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6860632 | 0.86 | ARG1 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL8144169 | 0.85 | CHRM2 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL8156937 | 0.85 | CHRM2 (0.33) | CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL28507729 | 0.82 | — | — | |
| SCHEMBL27383131 | 0.75 | DGAT1 (0.35) | DGAT1MEN1MAPK1KMT2A | |
| SCHEMBL8144279 | 0.75 | ARG1 (0.32) | — | |
| SCHEMBL16759576 | 0.73 | GAA (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074386-A1 | NOVEL AMINO PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015079417-A1 | NOVEL AMINO PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-06-04 | — | — | WO | disclosed |