Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.33 |
| ▸ | ARG2 | P78540 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519878 | 1.00 | ARG1 (0.33) | ARG1ARG2CHRM2CHRM1CHRM3 | |
| SCHEMBL16759533 | 0.86 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL16759581 | 0.86 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL16759709 | 0.86 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL10669809 | 0.84 | — | — | |
| SCHEMBL28476403 | 0.84 | — | — | |
| SCHEMBL7286719 | 0.78 | ARG1 (0.42) | ARG1ARG2 | |
| SCHEMBL6422818 | 0.76 | — | — | |
| SCHEMBL29548435 | 0.76 | CTSK (0.34) | — | |
| SCHEMBL221457 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |