SCHEMBL16760375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29427066	1.00	TDP1 (0.50)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL2892314	0.88	MAPT (0.58)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL26641106	0.82	MAPK1 (0.44)	TDP1L3MBTL1MAPK1MRGPRX4RXRA
	SCHEMBL29628710	0.81	MAPK14 (0.45)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL2893555	0.81	MAPK14 (0.43)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL20607341	0.81	MAPK14 (0.45)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL1513408	0.81	MAPT (0.57)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL27402197	0.81	MAPT (0.50)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL16760350	0.81	MAPK14 (0.50)	TDP1L3MBTL1MAPTMAPK1MAPK14
	SCHEMBL1081189	0.79	MAPT (0.59)	TDP1L3MBTL1MAPTMAPK1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.