SCHEMBL16760892

SCHEMBL16760892

Bc1ccc(F)cc1.CC(C)NC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
TRPA1 O75762 1/20 0.36
KCNH3 Q9ULD8 2/20 0.36
ACHE P22303 1/20 0.36
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
HPGD P15428 2/20 0.32
ALDH1A1 P00352 2/20 0.32
APEX1 P27695 1/20 0.31
PMP22 Q01453 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2430178 0.79
SCHEMBL16760912 0.78 ACHE (0.40) TDP1KCNH3ACHECA1CA2
SCHEMBL16760902 0.76 TDP1 (0.38) TDP1CA1CA9
SCHEMBL11019482 0.76
SCHEMBL16760869 0.76 SLC6A2 (0.34) TDP1
SCHEMBL16760914 0.76 KIF11 (0.44) KCNH3CA1CA2ALDH1A1
SCHEMBL16760905 0.74 CA3 (0.35) TDP1ALDH1A1CA9
SCHEMBL16760890 0.73 CA1 (0.48) TDP1KCNH3ACHECA1CA2
SCHEMBL17465581 0.71 IDO1 (0.38) KCNH3ACHEALDH1A1HTTMEN1
SCHEMBL14561176 0.71 HTT (0.46) CYP2D6ALDH1A1ADRB2HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2881398-A1 Method for preparing aminoarylborane compounds or derivatives thereof Université de Bordeaux I (FR) 2015-06-10 EP disclosed