Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036679 | 0.73 | — | — | |
| SCHEMBL10691956 | 0.65 | KDM4E (0.39) | ALDH1A1POLBTUBB4ATUBBTUBA3C | |
| SCHEMBL28049111 | 0.61 | GRM6 (0.36) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL20684280 | 0.61 | L3MBTL1 (0.46) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10844900 | 0.60 | CA12 (0.44) | PDE4BALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL11331212 | 0.60 | KDM4E (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL12181771 | 0.59 | PDE4B (0.71) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL18775276 | 0.59 | PDE4B (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL26173373 | 0.59 | MAPT (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL21724837 | 0.58 | NOTUM (0.41) | ALDH1A1ALOX5POLBGRM6GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611281-B2 | BODIPY derivatives and methods of synthesis and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150158888-A1 | BODIPY Derivatives and Methods of Synthesis and Use Thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158888-A1 | BODIPY Derivatives and Methods of Synthesis and Use Thereof | FDPS, FDFT1, BCR | PDE4A 4028/4885PDE4B 3598/4885PDE4C 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.