Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238880 | 0.67 | FYN (0.60) | KDM4EALDH1A1HPGDCTDSP1FYN | |
| SCHEMBL16763232 | 0.65 | PDE4A (0.35) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9869471 | 0.64 | BRAF (0.37) | KDM4EALDH1A1HPGDCTDSP1EGFR | |
| SCHEMBL11331212 | 0.64 | KDM4E (0.40) | KDM4EALDH1A1HPGDFYNEGFR | |
| SCHEMBL10744711 | 0.64 | HSP90AA1 (0.44) | KDM4EALDH1A1HPGDMAPK1KMT2A | |
| SCHEMBL11521411 | 0.63 | HSD17B1 (0.48) | KDM4EALDH1A1HPGDFYNEGFR | |
| SCHEMBL4396043 | 0.62 | ACHE (0.48) | KDM4EALDH1A1HPGDFYNBRAF | |
| Methoxy Aucuparin SCHEMBL8420787 | 0.62 | KDM4E (0.62) | KDM4EALDH1A1HPGDCTDSP1FYN | |
| Dimethylamine SCHEMBL619459 | 0.62 | FYN (0.50) | KDM4EALDH1A1HPGDCTDSP1FYN | |
| SCHEMBL28338665 | 0.61 | HPGD (0.61) | KDM4EALDH1A1HPGDCTDSP1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767766-A | Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1988-08-30 | — | — | US | disclosed |