SCHEMBL16765832

SCHEMBL16765832

NC1(C(O)(O)O)CCCC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647262 0.78 TSHR (0.31) TSHRCYP2C19
SCHEMBL12133518 0.75 TSHR (0.35) TSHRCYP2C19
Hydrochloric Acid SCHEMBL1350431 0.75
SCHEMBL12133516 0.71
SCHEMBL8673856 0.68 TSHR (0.44) TSHRCYP2C19
SCHEMBL3431977 0.67
SCHEMBL1792526 0.67
SCHEMBL24760385 0.65
SCHEMBL28950862 0.65
SCHEMBL28540349 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137256-A1 POLYOXAZOLINE-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2025-06-26 WO disclosed
EP-3313857-B1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES WU NIAN (US) 2021-01-06 EP disclosed
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPOSEUTICALS INC 2020-11-17 US disclosed
EP-3077006-B1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2020-08-19 EP disclosed
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates LIPOSEUTICALS INC 2018-09-04 US disclosed
EP-3313857-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES Wu, Nian (US) 2018-05-02 EP disclosed
WO-2016209732-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES WU NIAN (US) 2016-12-29 WO disclosed
US-20160375150-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES LIPOSEUTICALS INC 2016-12-29 US disclosed
EP-3077006-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY Wu, Nian (US) 2016-10-12 EP disclosed
WO-2015085173-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2015-06-11 WO disclosed
US-20150157721-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY LIPOSEUTICALS INC 2015-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPC, FABP4, CETP TSHR 2812/4885CYP2C19 93/4885
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates CETP, FABP4, PLIN3 TSHR 3583/4885CYP2C19 54/4885
US-20150157721-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY LIPC, FABP4, CETP TSHR 2812/4885CYP2C19 93/4885
US-20160375150-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES CETP, FADS2, FABP4 TSHR 3545/4885CYP2C19 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.