Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16768044 | 0.76 | MEN1 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16768138 | 0.75 | HRH1 (0.38) | SMN1; SMN2ALDH1A1HRH1HPGD | |
| SCHEMBL11926965 | 0.73 | HRH1 (0.45) | HRH1GAANPC1POLB | |
| SCHEMBL5524100 | 0.72 | HSD17B10 (0.56) | SMN1; SMN2ALDH1A1LMNAHRH1GAA | |
| SCHEMBL21448896 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10223189 | 0.71 | HRH1 (0.44) | SMN1; SMN2ALDH1A1HRH1HPGD | |
| SCHEMBL21419245 | 0.70 | HRH1 (0.43) | ALDH1A1HRH1MAPT | |
| SCHEMBL1421878 | 0.69 | RAB9A (0.60) | SMN1; SMN2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL21448897 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1HRH1 | |
| SCHEMBL7079640 | 0.68 | HRH1 (0.42) | SMN1; SMN2ALDH1A1HRH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152096-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152096-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | DPYD, SLC10A1, HPRT1 | SMN1; SMN2 1778/4885MEN1 1746/4885KMT2A 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.