Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16768694 | 0.84 | NAMPT (0.40) | OPRK1FDPSKMT2AMEN1TRPM5 | |
| SCHEMBL16768679 | 0.81 | ADORA3 (0.39) | OPRK1 | |
| SCHEMBL16133684 | 0.81 | MAPT (0.49) | OPRK1FDPSKMT2AMEN1TRPM5 | |
| SCHEMBL13212926 | 0.75 | FDPS (0.45) | OPRK1FDPSKMT2AMEN1TRPM5 | |
| SCHEMBL13734058 | 0.75 | FDPS (0.49) | OPRK1FDPSKMT2AMEN1TRPM5 | |
| SCHEMBL3396713 | 0.75 | OPRK1 (0.46) | OPRK1FDPSKMT2AMEN1TRPM5 | |
| SCHEMBL4150247 | 0.74 | OPRK1 (0.43) | OPRK1FDPSKMT2AMEN1TRPM5 | |
| SCHEMBL21765308 | 0.73 | — | — | |
| SCHEMBL5127427 | 0.73 | — | — | |
| SCHEMBL1797127 | 0.73 | OPRK1 (0.45) | OPRK1FDPSKMT2AMEN1TRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045477-B2 | Substituted 6,5-fused bicyclic heteroaryl compounds | Epizyme, Inc. (US) | 2015-06-02 | — | — | US | disclosed |