Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799649 | 0.94 | SIGMAR1 (0.65) | SIGMAR1TDP1MEN1KMT2AGAA | |
| SCHEMBL23775760 | 0.89 | SIGMAR1 (0.63) | SIGMAR1TDP1MEN1KMT2AGAA | |
| SCHEMBL17742668 | 0.84 | SIGMAR1 (0.58) | SIGMAR1TDP1MEN1KMT2AGAA | |
| SCHEMBL9354347 | 0.84 | SIGMAR1 (0.56) | SIGMAR1TDP1MEN1KMT2AGAA | |
| SCHEMBL4422293 | 0.84 | SIGMAR1 (0.55) | SIGMAR1TDP1MEN1KMT2AGAA | |
| SCHEMBL1929294 | 0.83 | NR2F2 (0.60) | SIGMAR1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1930614 | 0.83 | NR2F2 (0.60) | SIGMAR1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL28329409 | 0.82 | SIGMAR1 (0.54) | SIGMAR1TDP1MEN1KMT2AGAA | |
| SCHEMBL25148116 | 0.82 | SIGMAR1 (0.53) | SIGMAR1TDP1ALDH1A1NR2F2RAB9A | |
| SCHEMBL13369184 | 0.81 | SIGMAR1 (0.55) | SIGMAR1TDP1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9044478-B2 | Use of 1,4-bis (3-aminoalkyl) piperazine derivatives in the treatment of neurodegenerative diseases | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2015-06-02 | — | — | US | disclosed |