SCHEMBL16769694 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	ADK	P55263	6/20	0.47

▸	RET	P07949	8/20	0.38

▸	KIF5B	P33176	7/20	0.38

▸	KDR	P35968	5/20	0.38

▸	METTL3	Q86U44	4/20	0.38

▸	KCNH2	Q12809	1/20	0.36

▸	CCDC6	Q16204	1/20	0.36

▸	ABL1	P00519	1/20	0.34

▸	NTRK1	P04629	1/20	0.34

▸	LCK	P06239	1/20	0.34

▸	LYN	P07948	1/20	0.34

▸	KIT	P10721	1/20	0.34

▸	BCR	P11274	1/20	0.34

▸	SRC	P12931	1/20	0.34

▸	BLK	P51451	1/20	0.34

▸	NTRK2	Q16620	1/20	0.34

▸	IRAK4	Q9NWZ3	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18925738	1.00	ADK (0.47)	ADKRETKIF5BKDRMETTL3
SCHEMBL18925745	0.85	METTL3 (0.50)	ADKRETKIF5BKDRMETTL3
SCHEMBL16769693	0.85	METTL3 (0.50)	ADKRETKIF5BKDRMETTL3
SCHEMBL29780875	0.83	ADK (0.52)	ADKRETKDRMETTL3ABL1
SCHEMBL16769982	0.83	ADK (0.52)	ADKRETKDRMETTL3ABL1
SCHEMBL1444354	0.81	RET (0.58)	ADKRETKIF5BKDRKCNH2
SCHEMBL1441871	0.81	RET (0.58)	ADKRETKIF5BKDRKCNH2
SCHEMBL1441873	0.81	RET (0.58)	ADKRETKIF5BKDRKCNH2
SCHEMBL868173	0.80	ADK (0.54)	ADKRETMETTL3LCKSRC
SCHEMBL1443270	0.80	ADK (0.43)	ADKRETKIF5BKDRMETTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015077866-A1	PROTEIN KINASE INHIBITORS	PHARMASCIENCE INC. (CA)	2015-06-04	—	—	WO	disclosed