Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 10/20 | 0.50 |
| ▸ | ADK | P55263 | 4/20 | 0.47 |
| ▸ | RET | P07949 | 5/20 | 0.45 |
| ▸ | KIF5B | P33176 | 4/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18925745 | 1.00 | METTL3 (0.50) | METTL3ADKRETKIF5BKDR | |
| SCHEMBL18925738 | 0.85 | ADK (0.47) | METTL3ADKRETKIF5BKDR | |
| SCHEMBL16769694 | 0.85 | ADK (0.47) | METTL3ADKRETKIF5BKDR | |
| SCHEMBL16769984 | 0.83 | RET (0.58) | METTL3ADKRETKDRABL1 | |
| SCHEMBL29780883 | 0.83 | RET (0.58) | METTL3ADKRETKDRABL1 | |
| SCHEMBL1444001 | 0.81 | RET (0.69) | METTL3ADKRETKIF5BKDR | |
| SCHEMBL1444002 | 0.81 | RET (0.69) | METTL3ADKRETKIF5BKDR | |
| SCHEMBL870154 | 0.80 | METTL3 (0.58) | METTL3ADKRETKDRABL1 | |
| SCHEMBL1442891 | 0.80 | RET (0.46) | METTL3ADKRETKIF5BKDR | |
| SCHEMBL16769992 | 0.79 | ABL1 (0.63) | METTL3ADKKDRABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077866-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-06-04 | — | — | WO | disclosed |