SCHEMBL16769855

SCHEMBL16769855

C[C@@H]1CCC2(OC2(C)C)C(=O)C1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9445749 1.00 MEN1 (0.34) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL8678507 0.74 MEN1 (0.39) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL10591170 0.68 CRBN (0.50) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL11911681 0.67 PRKCA (0.33) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL7751354 0.67 ALDH1A1 (0.36) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL28676565 0.67 ALDH1A1 (0.36) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL6755435 0.66 KMT2A (0.35) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL19264444 0.66 KMT2A (0.35) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL14895194 0.65 MEN1 (0.32) MEN1ALDH1A1LMNAMAPTKMT2A
SCHEMBL5868539 0.63 CRBN (0.31) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220280582-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2022-09-08 US disclosed
US-11344591-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2022-05-31 US disclosed
US-11331358-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2022-05-17 US disclosed
US-20200246405-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CURE PHARMACEUTICAL HOLDING CORP. (US) 2020-08-06 US disclosed
US-20200197466-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CURE PHARMACEUTICAL HOLDING CORP (US) 2020-06-25 US disclosed
US-10639339-B2 Pharmaceutical composition and method of manufacturing CURE PHARMACEUTICAL HOLDING CORP. (US) 2020-05-05 US disclosed
US-10624940-B2 Pharmaceutical composition and method of manufacturing CURE PHARMACEUTICAL HOLDING CORP. (US) 2020-04-21 US disclosed
US-20190209633-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2019-07-11 US disclosed
US-10238705-B2 Pharmaceutical composition and method of manufacturing CURE PHARMACEUTICAL HOLDING CORP. (US) 2019-03-26 US disclosed
US-20190030103-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2019-01-31 US disclosed
US-20160074451-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2016-03-17 US disclosed
US-20160074451-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2016-03-17 US disclosed
US-9186386-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2015-11-17 US disclosed
US-9186386-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2015-11-17 US disclosed
US-20150297653-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2015-10-22 US disclosed
US-20150297653-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2015-10-22 US disclosed
US-20150297654-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2015-10-22 US disclosed
US-20150297654-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2015-10-22 US disclosed
US-9044390-B1 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2015-06-02 US disclosed
US-9044390-B1 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2015-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246405-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-10639339-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-10238705-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-11344591-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-11331358-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20160074451-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20150297654-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20220280582-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20190030103-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20150297653-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20200197466-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-20190209633-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885
US-10624940-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 MEN1 3386/4885ALDH1A1 4647/4885LMNA 4008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.